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- 190articles · 30d
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News
Cefepime Tied to Higher Mortality Odds vs Other Beta-Lactams
3+ day, 21+ hour ago (135+ words) The danger may be in the dosing, not in the drug itself...
IL-33 Inhibitor Delivers in COPD Trials
4+ day, 15+ hour ago (661+ words) — Tozorakimab highly promising as biologic therapy in replicate phase III trials A broad population of people with chronic obstructive pulmonary disease (COPD), current and former smokers alike, experienced fewer exacerbations taking a first-in-class biologic targeting interleukin (IL)-33, a pair of…...
H. Pylori Exposure and Colorectal Cancer: The Evidence Grows
4+ day, 15+ hour ago (614+ words) — Modeling study suggests an association Exposure to Helicobacter pylori, known for its role in gastric cancer, may also play a role in colorectal cancer (CRC), according to results from a risk-attribution modeling study. Based on estimates from 43 studies, H. pylori…...
Is Paxlovid Any Better Than Placebo for Long COVID?
1+ week, 3+ day ago (181+ words) In three major symptom phenotypes, randomized trial finds no benefit...
Dramatic Improvement in Dermatomyositis Skin Symptoms With First Approved Oral Agent
1+ week, 3+ day ago (29+ words) Lesion clearance rate, itch reduction doubled with TYK2/JAK1 inhibitor brepocitinib...
FDA Adds Boxed Warning to Iron Replacement Injection
1+ week, 5+ day ago (167+ words) — Label change for ferric carboxymaltose warns of risk for symptomatic hypophosphatemia The FDA approved a label change for ferric carboxymaltose injection (Injectafer) that adds a boxed warning for the risk of symptomatic hypophosphatemia. The agency recommends monitoring of phosphate levels…...
GLP-1 Drugs Tied to Gallbladder and Biliary Risks in Youth
1+ week, 6+ day ago (427+ words) — Real-world study identifies safety signal in young people with overweight or obesity Use of GLP-1 receptor agonists was associated with increased cumulative gallbladder and biliary events in youths, according to a retrospective analysis of TriNetX data. Among over 37,000 adolescents and…...
FDA Expands Label of Oral HIV Drug to Newborns
2+ week, 4+ day ago (12+ words) Dolutegravir is already approved as combination therapy in adults and older children...
Inpatient Continuous Glucose Monitor Alerts Show Mixed Results in Trial
3+ week, 3+ day ago (510+ words) — Threshold alerts modestly helped, but predictive alerts fell flat Continuous glucose monitoring (CGM) threshold alerts modestly improved inpatient glycemic control, but adding predictive alerts provided no further benefit, a three-arm trial showed. Among 533 adults with type 1 or type 2 diabetes admitted…...
Dramatic Increase in Active Surveillance Use for Prostate Cancer
3+ week, 4+ day ago (412+ words) — Soared past 90% in VA system for low-risk disease, to 61% for favorable intermediate-risk disease Use of active surveillance for low- and favorable intermediate-risk prostate cancer more than tripled since 2005, according to a large study of veterans. In 2005 active surveillance accounted for…...